abstract：:Amazonian puffing snakes (Spilotes; Colubridae) are snakes widely distributed in the Neotropical region. However, chromosomal data are scarce in this group and, when available, are only limited to karyotype description using conventional staining. In this paper, we focused on the process of karyotype evolution and tre...

journal_title：Genes

authors： Viana PF,Ezaz T,de Bello Cioffi M,Jackson Almeida B,Feldberg E

更新日期：2019-04-09 00:00:00

abstract：:Quorum sensing (QS) is a cell-to-cell communication system that uses autoinducers as signaling molecules to enable inter-species and intra-species interactions in response to external stimuli according to the population density. QS allows bacteria such as Acinetobacter baumannii to react rapidly in response to environ...

journal_title：Genes

authors： Ng CK,How KY,Tee KK,Chan KG

更新日期：2019-04-08 00:00:00

abstract：:The spread of food allergens is a topic of global importance due to its impact on public health. National and International regulations ask food producers and manufacturers to declare product compositions on the label, especially in case of processed raw materials. Wheat flour (Triticum aestivum) can be contaminated b...

journal_title：Genes

authors： Frigerio J,Pellesi R,Mezzasalma V,De Mattia F,Galimberti A,Lambertini F,Suman M,Zanardi S,Leporati A,Labra M

更新日期：2019-03-19 00:00:00

abstract：:The increasing availability of large-scale time series data allows the inference of microbial community dynamics by association network analysis. However, correlation-based association network analyses are noninformative of causal, mediating and time-dependent relationships between microbial community functional facto...

journal_title：Genes

authors： Ai D,Li X,Liu G,Liang X,Xia LC

更新日期：2019-03-14 00:00:00

abstract：:The woody Sonchus alliance consists primarily of woody species of the genus Sonchus (subgenus Dendrosonchus; family Asteraceae). Most members of the alliance are endemic to the oceanic archipelagos in the phytogeographic region of Macaronesia. They display extensive morphological, ecological, and anatomical diversity,...

journal_title：Genes

authors： Cho MS,Yang JY,Yang TJ,Kim SC

更新日期：2019-03-14 00:00:00

abstract：:Chinese kale is a native vegetable in Southern China and the flowering stalk is the most commonly used edible part due to its high glucosinolate content and other nutritional qualities. The GTR protein played important roles in the glucosinolate transport process. In this study, three BocGTR1 genes were cloned from Ch...

journal_title：Genes

authors： Jiang D,Lei J,Cao B,Wu S,Chen G,Chen C

更新日期：2019-03-08 00:00:00

abstract：:The Zn(II)₂Cys₆ zinc cluster gene family is a subclass of zinc-finger proteins, which are transcriptional regulators involved in a wide variety of biological processes in fungi. We performed genome-wide identification and characterization of Zn(II)₂Cys₆ zinc-cluster gene (C6 zinc gene) family in Tolypocladiumguangdong...

journal_title：Genes

authors： Zhang C,Huang H,Deng W,Li T

更新日期：2019-02-26 00:00:00

abstract：:In cystic fibrosis (CF), mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene disrupt the capacity of the encoded protein to function as a channel to transport chloride ions and water across cell membranes. The consequences are deleterious, system-wide, and immensely variable, even among pa...

journal_title：Genes

authors： Ideozu JE,Zhang X,McColley S,Levy H

更新日期：2019-02-26 00:00:00

abstract：:Olfaction, which is mediated by olfactory receptor (OR) genes, is essential in the daily life of fish, especially in foraging. However, Chinese perch (Siniperca chuatsi) is believed to prey with reliance on vision and lateral sensation, but not on olfaction. Therefore, understanding the evolutionary dynamics of the Ch...

journal_title：Genes

authors： Lv LY,Liang XF,He S

更新日期：2019-02-25 00:00:00

abstract：:This review discusses a set of experimental results that support the existence of extended strand displacement events during budding yeast lagging strand DNA synthesis. Starting from introducing the mechanisms and factors involved in leading and lagging strand DNA synthesis and some aspects of the architecture of the ...

journal_title：Genes

authors： Giannattasio M,Branzei D

更新日期：2019-02-21 00:00:00

abstract：:Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi [...]. ...

journal_title：Genes

authors： Houben A,Jones N,Martins C,Trifonov V

更新日期：2019-02-20 00:00:00

abstract：:Circadian clocks in eukaryotes involve both transcriptional-translational feedback loops, post-translational regulation, and metabolic, non-transcriptional oscillations. We recently identified the involvement of circadian oscillations in the intracellular concentrations of magnesium ions (Mg2+i) that were conserved in...

journal_title：Genes

authors： Feord HK,Dear FEG,Obbard DJ,van Ooijen G

更新日期：2019-02-19 00:00:00

abstract：:In the frog genus Pseudis, previous works found a sex-linked heteromorphism of the PcP190 satellite DNA in the nucleolus organizer region (NOR)-bearing chromosome pairs of Pseudis bolbodactyla and Pseudis tocantins, which possess a ZZ/ZW sex determination system. A pericentromeric inversion was inferred to have occurr...

journal_title：Genes

authors： Gatto KP,Seger KR,Garcia PCA,Lourenço LB

更新日期：2019-02-19 00:00:00

abstract：:Ehlers-Danlos syndrome (EDS) comprises clinically heterogeneous connective tissue disorders with diverse molecular etiologies. The 2017 International Classification for EDS recognized 13 distinct subtypes caused by pathogenic variants in 19 genes mainly encoding fibrillar collagens and collagen-modifying or processing...

journal_title：Genes

authors： Ritelli M,Cinquina V,Venturini M,Pezzaioli L,Formenti AM,Chiarelli N,Colombi M

更新日期：2019-02-12 00:00:00

abstract：:Approximately 150 fungal species are considered as primary pathogens of humans and animals[...]. ...

journal_title：Genes

authors： Leal F

更新日期：2019-02-12 00:00:00

abstract：:B chromosomes are enigmatic heritable elements found in the genomes of numerous plant and animal species. Contrary to their broad distribution, most B chromosomes are non-essential. For this reason, they are regarded as genome parasites. In order to be stably transmitted through generations, many B chromosomes exhibit...

journal_title：Genes

authors： Dalla Benetta E,Akbari OS,Ferree PM

更新日期：2019-02-08 00:00:00

abstract：:Biogerontological research highlighted a complex and dynamic connection between aging, health and longevity, partially determined by genetic factors. Multifunctional proteins with moonlighting features, by integrating different cellular activities in the space and time, may explain part of this complexity. Inositol Po...

journal_title：Genes

authors： De Rango F,Crocco P,Iannone F,Saiardi A,Passarino G,Dato S,Rose G

更新日期：2019-02-08 00:00:00

abstract：:We studied and compared the nucleolar expression or nucleoli from specific bivalents in spermatocytes of the standard Mus musculus domesticus 2n=40, of Robertsonian (Rb) homozygotes 2n = 24 and heterozygotes 2n = 32. We analyzed 200 nuclear microspreads of each specific nucleolar chromosome and spermatocyte karyotype,...

journal_title：Genes

authors： López-Moncada F,Tapia D,Zuñiga N,Ayarza E,López-Fenner J,Redi CA,Berríos S

更新日期：2019-02-06 00:00:00

abstract：:Marek's Disease is a lymphoproliferative disease of chickens caused by Marek's Disease Virus. Similar to other herpesviruses, Marek's Disease Virus (MDV) encodes its own small non-coding regulatory RNAs termed microRNAs (miRNAs). We previously found that the expression profile of these viral miRNAs is affected by vacc...

journal_title：Genes

authors： Hicks JA,Liu HC

更新日期：2019-02-05 00:00:00

abstract：:Repetitive DNA including tandem repeats (TRs) is a significant part of most eukaryotic genomes. TRs include rapidly evolving satellite DNA (satDNA) that can be shared by closely related species, their abundance may be associated with evolutionary divergence, and they have been widely used for chromosome karyotyping us...

journal_title：Genes

authors： Kroupin P,Kuznetsova V,Romanov D,Kocheshkova A,Karlov G,Dang TX,Khuat TML,Kirov I,Alexandrov O,Polkhovskiy A,Razumova O,Divashuk M

更新日期：2019-02-01 00:00:00

abstract：:Self/foreign discrimination by the innate immune system depends on receptors that identify molecular patterns as associated to pathogens. Among others, this group includes endosomal Toll-like receptors, among which Toll-like receptors (TLR) 3, 7, 8, and 13 recognize and discriminate mammalian from microbial, potential...

journal_title：Genes

authors： Freund I,Eigenbrod T,Helm M,Dalpke AH

更新日期：2019-01-29 00:00:00

abstract：:Single-cell RNA sequencing (scRNA-seq) has recently brought new insight into cell differentiation processes and functional variation in cell subtypes from homogeneous cell populations. A lack of prior knowledge makes unsupervised machine learning methods, such as clustering, suitable for analyzing scRNA-seq . However,...

journal_title：Genes

authors： Zhu X,Li HD,Xu Y,Guo L,Wu FX,Duan G,Wang J

更新日期：2019-01-29 00:00:00

abstract：:Advances in sequencing technologies have enabled the exploration of the genetic basis for several clinical disorders by allowing identification of causal mutations in rare genetic diseases. Sequencing technology has also facilitated genome-wide association studies to gather single nucleotide polymorphisms in common di...

journal_title：Genes

authors： Romanowska J,Joshi A

更新日期：2019-01-23 00:00:00

abstract：:Loss of seed shattering is a key trait in crop domestication, particularly for grain crops. For wild plants, seed shattering is a crucial mechanism to achieve greater fitness, although in the agricultural context, this mechanism reduces harvesting efficiency, especially under dry conditions. Loss of seed shattering wa...

journal_title：Genes

authors： Di Vittori V,Gioia T,Rodriguez M,Bellucci E,Bitocchi E,Nanni L,Attene G,Rau D,Papa R

更新日期：2019-01-19 00:00:00

abstract：:DNA methylation, catalyzed by DNA methyltransferases (DNMTs), is an epigenetic mark that needs to be faithfully replicated during mitosis in order to maintain cell phenotype during successive cell divisions. This epigenetic mark is located on the 5'-carbon of the cytosine mainly within cytosine⁻phosphate⁻guanine (CpG)...

journal_title：Genes

authors： Bronner C,Alhosin M,Hamiche A,Mousli M

更新日期：2019-01-18 00:00:00

abstract：:In contrast to the amazing exponential growth in knowledge related to long non-coding RNAs (lncRNAs) involved in cell homeostasis or dysregulated pathological states, little is known so far about the links between the chemical modifications occurring in lncRNAs and their function. Generally, ncRNAs are post-transcript...

journal_title：Genes

authors： Dinescu S,Ignat S,Lazar AD,Constantin C,Neagu M,Costache M

更新日期：2019-01-16 00:00:00

abstract：:Cystic fibrosis (CF) is an inherited monogenic disorder, amenable to gene-based therapies. Because CF lung disease is currently the major cause of mortality and morbidity, and the lung airway is readily accessible to gene delivery, the major CF gene therapy effort at present is directed to the lung. Although airway ep...

journal_title：Genes

authors： Xia E,Zhang Y,Cao H,Li J,Duan R,Hu J

更新日期：2019-01-11 00:00:00

abstract：:N6-methyladenosine (m6A) is the most abundant RNA modification. It has been involved in the regulation of RNA metabolism, including degradation and translation, in both physiological and disease conditions. A recent study showed that m6A-mediated degradation of key transcripts also plays a role in the control of T cel...

journal_title：Genes

authors： Furlan M,Galeota E,de Pretis S,Caselle M,Pelizzola M

更新日期：2019-01-08 00:00:00

abstract：:The superior performance of hybrids to parents, termed heterosis, has been widely utilized in animal and plant breeding programs, but the molecular mechanism underlying heterosis remains an enigma. RNA-Seq provides a novel way to investigate heterosis at the transcriptome-wide level, because gene expression functions ...

journal_title：Genes

authors： Zhuo Z,Lamont SJ,Abasht B

更新日期：2019-01-07 00:00:00

abstract：:The integration of phenotypes and genotypes is at an unprecedented level and offers new opportunities to establish deep phenotypes. There are a number of challenges to overcome, specifically, accelerated growth of data, data silos, incompleteness, inaccuracies, and heterogeneity within and across data sources. This pe...

journal_title：Genes

authors： Frey LJ

更新日期：2018-12-28 00:00:00

abstract：:Epigenetic modifications are a mechanism conveying environmental information to subsequent generations via parental germ lines. Research on epigenetic responses to environmental changes in wild mammals has been widely neglected, as well as studies that compare responses to changes in different environmental factors. H...

journal_title：Genes

authors： Weyrich A,Lenz D,Fickel J

更新日期：2018-12-21 00:00:00

abstract：:The obligately anaerobic haloalkaliphilic bacterium Alkalitalea saponilacus can use xylan as the sole carbon source and produce propionate as the main fermentation product. Using mixed carbon sources of 0.4% (w/v) sucrose and 0.1% (w/v) birch xylan, xylanase production from A. saponilacus was 3.2-fold greater than tha...

journal_title：Genes

authors： Liao Z,Holtzapple M,Yan Y,Wang H,Li J,Zhao B

更新日期：2018-12-20 00:00:00

abstract：:Metabolic resistance to insecticides threatens malaria control. However, little is known about its fitness cost in field populations of malaria vectors, thus limiting the design of suitable resistance management strategies. Here, we assessed the association between the glutathione S-transferase GSTe2-mediated metaboli...

journal_title：Genes

authors： Tchouakui M,Riveron JM,Djonabaye D,Tchapga W,Irving H,Soh Takam P,Njiokou F,Wondji CS

更新日期：2018-12-19 00:00:00

abstract：:Inherited retinal degenerations are the leading cause of blindness in the working population. X-linked retinitis pigmentosa (XLRP), caused by mutations in the Retinitis pigmentosa GTPase regulator (RPGR) gene is one of the more severe forms, and female carriers of RPGR mutations have a variable presentation. A retrosp...

journal_title：Genes

authors： Nanda A,Salvetti AP,Clouston P,Downes SM,MacLaren RE

更新日期：2018-12-18 00:00:00

abstract：:DNA double-strand breaks (DSBs) jeopardize genome integrity and can-when repaired unfaithfully-give rise to structural rearrangements associated with cancer. Exogenous agents such as ionizing radiation or chemotherapy can invoke DSBs, but a vast amount of breakage arises during vital endogenous DNA transactions, such ...

journal_title：Genes

authors： Bouwman BAM,Crosetto N

更新日期：2018-12-14 00:00:00

abstract：:The accurate repair of DNA is critical for genome stability and cancer prevention. DNA double-strand breaks are one of the most toxic lesions; however, they can be repaired using homologous recombination. Homologous recombination is a high-fidelity DNA repair pathway that uses a homologous template for repair. One cen...

journal_title：Genes

authors： Sullivan MR,Bernstein KA

更新日期：2018-12-13 00:00:00

abstract：:The rapid accumulation of ancient human genomes from various areas and time periods potentially enables the expansion of studies of biodiversity, biogeography, forensics, population history, and epidemiology into past populations. However, most ancient DNA (aDNA) data were generated through microarrays designed for mo...

journal_title：Genes

authors： Esposito U,Das R,Syed S,Pirooznia M,Elhaik E

更新日期：2018-12-12 00:00:00

abstract：:Transfer RNAs (tRNAs) are abundant small non-coding RNAs that are crucially important for decoding genetic information. Besides fulfilling canonical roles as adaptor molecules during protein synthesis, tRNAs are also the source of a heterogeneous class of small RNAs, tRNA-derived small RNAs (tsRNAs). Occurrence and th...

journal_title：Genes

authors： Oberbauer V,Schaefer MR

更新日期：2018-12-05 00:00:00

abstract：:B chromosomes (Bs) were discovered a century ago, and since then, most studies have focused on describing their distribution and abundance using traditional cytogenetics. Only recently have attempts been made to understand their structure and evolution at the level of DNA sequence. Many questions regarding the origin,...

journal_title：Genes

authors： Clark FE,Conte MA,Kocher TD

更新日期：2018-12-05 00:00:00

abstract：:The grizzly bear (Ursus arctos ssp. horribilis) represents the largest population of brown bears in North America. Its genome was sequenced using a microfluidic partitioning library construction technique, and these data were supplemented with sequencing from a nanopore-based long read platform. The final assembly was...

journal_title：Genes

authors： Taylor GA,Kirk H,Coombe L,Jackman SD,Chu J,Tse K,Cheng D,Chuah E,Pandoh P,Carlsen R,Zhao Y,Mungall AJ,Moore R,Birol I,Franke M,Marra MA,Dutton C,Jones SJM

更新日期：2018-11-30 00:00:00